The anti-spam plugin I’d been using has been discontinued by its author, so I’ve switched to a different one that seems highly recommended.
E-mail me (or send me a message via Twitter) if you notice any problems commenting, logging in, etc.
I considered adding Google’s new CAPTCHA-less reCAPTCHA, but decided to hold off on that unless it proves absolutely necessary.
The new plugin requires that JavaScript and cookies be enabled, but I believe that was already the case.